New technique could transform epigenetics research
(Medical Xpress) -- Collaboration between scientists at Cambridge University and the Babraham Institute have demonstrated a new technique that will significantly improve scientists' ability to perform...
View ArticleNew research sheds light on the molecular mechanisms by which a virus...
Hepatocellular carcinoma (HCC) is the third leading cause of cancer deaths worldwide and is associated with exposure to hepatitis B virus (HBV). Patients carrying the virus have a 100-fold greater risk...
View ArticleUnlocking the secrets of DNA repair
Scientists from the University of Sheffield have unlocked one of the secrets to DNA repair—helping doctors identify DNA base damage and a patient's susceptibility to certain types of cancer.
View ArticleMeasuring enzyme levels in cancer patients may reveal healthy cells' ability...
New research from MIT may allow scientists to develop a test that can predict the severity of side effects of some common chemotherapy agents in individual patients, allowing doctors to tailor...
View ArticleTen years on, still much to be learned from human genome map
(HealthDay)—As scientists mark the 10th anniversary Sunday of the completion of the Human Genome Project, they will note how that watershed effort has led to the discovery of the genetic underpinnings...
View ArticleHow a protein "cancer cop" targets UV damage in DNA
Ah, summer. People are outside enjoying the warm weather, swimming, playing, or just soaking up that glorious, skin-damaging, high-energy UV radiation from the sun.
View ArticleA shift in the code: New method reveals hidden genetic landscape
With three billion letters in the human genome, it seems hard to believe that adding a DNA base here or removing a DNA base there could have much of an effect on our health. In fact, such insertions...
View ArticleThe evolution of human intellect: Human-specific regulation of neuronal genes
A new study published November 20 in the open-access journal PLOS Biology has identified hundreds of small regions of the genome that appear to be uniquely regulated in human neurons. These regulatory...
View ArticleProteins expressed by human cytomegalovirus mapped
(Medical Xpress)—A new study in the US and Germany has added to our understanding of the human cytomegalovirus (HCMV) and how it manipulates the cells it infects.
View ArticlePsychology professor seeks clues to psychiatric disorders in DNA
Data, data everywhere. In genomics research, there is a data deluge, so innovative ways to analyze all that information will play a critical role in future breakthroughs.
View ArticleCancer study overturns current thinking about gene activation
(Medical Xpress)—A new Australian study led by Professor Susan Clark from Sydney's Garvan Institute of Medical Research shows that large regions of the genome – amounting to roughly 2% – are...
View ArticleGenomic 'hotspots' offer clues to causes of autism, other disorders
An international team, led by researchers from the University of California, San Diego School of Medicine, has discovered that "random" mutations in the genome are not quite so random after all. Their...
View ArticleOne cell is all you need: Innovative technique can sequence entire genome...
The notion that police can identify a suspect based on the tiniest drop of blood or trace of tissue has long been a staple of TV dramas, but scientists at Harvard have taken the idea a step further....
View ArticleA scanner for hereditary defects
Our genetic material is constantly exposed to damage, which the body's own proteins normally repair. One of these proteins works like a scanner, continually scouring the genetic material for signs of...
View ArticleFrench police confounded by twins' DNA in rapes case
French police investigating a series of rapes in the southern city of Marseille are confounded after tracing DNA evidence to a set of twins but not knowing which one may be to blame.
View ArticleLife experiences put their stamp on the next generation: New insights from...
The 18th century natural philosopher Jean-Baptiste Lamarck proposed that the necks of giraffes lengthened as a consequence of the cumulative effort, across generations, to reach leaves just out of...
View ArticleDNA sequencing: Changing the landscape of science and biology
UConn researchers are at the forefront of new discoveries and understanding about the smallest molecules in the body that can have a momentous impact on human health.
View ArticleGene mutation as cause of breast and ovarian cancer
A change to the so-called TERT gene considerably increases the risk of breast and ovarian cancer. This is the result of a current, multicenter study in which the University Department of Gynaecology...
View ArticleLatino genomes point way to hidden DNA: 20 million missing base pairs mapped
Hidden in the tangled, repetitious folds of DNA structures called centromeres, researchers from Harvard Medical School and the Broad Institute have discovered the hiding place of 20 million base pairs...
View ArticleNew tool enhances the search for genetic mutations
Concealed within the vastness of the human genome, (comprised of some 3 billion base pairs), mutations are commonplace. While the majority of these appear to have neutral effect on human health, many...
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